Novobiocin, spiramycin, and aminitrozole in the treatment of non-gonococcal urethritis.
نویسنده
چکیده
During recent months, trials have been undertaken with three relatively new substances in the treatment of non-gonococcal urethritis in males. Two of these, novobiocin and spiramycin, are antibiotics. Novobiocin (also known as Streptonivicin, Albamycin, Cathomycin, Cathocin) has been prepared from the Streptomyces niveus and from Streptomyces spheroides and was developed in the United States. Also, it has been shown that Cardelmycin is the same substance. Spiramycin (Rovamycin), on the other hand, was developed in France and is prepared from the Streptomyces ambofaciens. The third substance, Aminitrozole (2-acetylamino-5-nitrothiazole), has been used successfully for some years to prevent enterohepatitis (blackhead disease) of turkeys. This condition is due to a flagellated protozoon, and in the USA some success has been claimed for the drug in human trichomoniasis. (This has not been substantiated by the writer who has had 100 per cent. of failures in sixteen female cases treated.) 87 previously untreated cases of non-gonococcal urethritis have been treated with spiramycin, forty with Novobiocin, and 49 with aminitrozole. The results are shown in Tables I to III.
منابع مشابه
Treatment of non-gonococcal urethritis.
With the increasing incidence of non-gonococcal urethritis (NGU), its treatment has assumed greater importance. The aetiology of NGU is far from clear but probably includes different factors; hence, it is not surprising that the response to treatment is so variable. The clinical picture in NGU also varies widely in severity. The mildest cases are sometimes difficult to distinguish from gonophob...
متن کامل[Treatment of non-gonococcal urethritis].
With the increasing incidence of non-gonococcal urethritis (NGU), its treatment has assumed greater importance. The aetiology of NGU is far from clear but probably includes different factors; hence, it is not surprising that the response to treatment is so variable. The clinical picture in NGU also varies widely in severity. The mildest cases are sometimes difficult to distinguish from gonophob...
متن کاملTreatment of non-gonococcal urethritis with tri-acetyl-oleandomycin.
The number of male cases of non-gonococcal urethritis (NGU) treated in the clinics of England and Wales continues to rise steadily each year, and have done so ever since figures were first published in 1951. The cause of the condition remains undiscovered and a variety of antibiotics, including the tetracyclines, spiramycin, erythromycin, and streptomycin (in conjunction with sulphonamides), ma...
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ورودعنوان ژورنال:
- The British journal of venereal diseases
دوره 33 3 شماره
صفحات -
تاریخ انتشار 1957